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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADAMTS6 All Species: 22.73
Human Site: S1013 Identified Species: 50
UniProt: Q9UKP5 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UKP5 NP_922932.2 1117 125273 S1013 P P V R I R C S L G R C P P P
Chimpanzee Pan troglodytes XP_526907 1117 125238 S1013 P P V R I R C S L G R C P P P
Rhesus Macaque Macaca mulatta XP_001084793 1117 125301 S1013 P P V R I R C S L G R C P P P
Dog Lupus familis XP_535255 1117 125043 S1013 P P V R I R C S L G R C P P P
Cat Felis silvestris
Mouse Mus musculus P58459 1104 121067 N998 P P S T M R C N L R R C P P A
Rat Rattus norvegicus Q1EHB3 1595 175796 P1473 L R P N N T R P C N T H P C T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513889 903 100601 L800 P T D E A E S L E A L G P T T
Chicken Gallus gallus XP_424749 1118 125075 S1014 P P V R I R C S L G R C P P P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001923204 1116 124633 S1012 P P V R I R C S L G R C P P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19791 2150 242563 C1789 A P T S I R E C D T S N C P Y
Sea Urchin Strong. purpuratus XP_001180742 1320 148448 N1133 P V Y R M P C N L G D C P P P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 99.6 98.4 N.A. 59.7 30.4 N.A. 72.9 92.4 N.A. 82.8 N.A. N.A. N.A. 21.4 39.7
Protein Similarity: 100 99.9 99.7 98.9 N.A. 74.4 41.5 N.A. 75.7 95.8 N.A. 90.1 N.A. N.A. N.A. 31.1 54.6
P-Site Identity: 100 100 100 100 N.A. 60 6.6 N.A. 13.3 100 N.A. 100 N.A. N.A. N.A. 26.6 60
P-Site Similarity: 100 100 100 100 N.A. 73.3 6.6 N.A. 13.3 100 N.A. 100 N.A. N.A. N.A. 26.6 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 10 0 0 0 0 10 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 73 10 10 0 0 73 10 10 0 % C
% Asp: 0 0 10 0 0 0 0 0 10 0 10 0 0 0 0 % D
% Glu: 0 0 0 10 0 10 10 0 10 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 64 0 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % H
% Ile: 0 0 0 0 64 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 0 0 0 0 0 10 73 0 10 0 0 0 0 % L
% Met: 0 0 0 0 19 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 10 0 0 19 0 10 0 10 0 0 0 % N
% Pro: 82 73 10 0 0 10 0 10 0 0 0 0 91 82 64 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 10 0 64 0 73 10 0 0 10 64 0 0 0 0 % R
% Ser: 0 0 10 10 0 0 10 55 0 0 10 0 0 0 0 % S
% Thr: 0 10 10 10 0 10 0 0 0 10 10 0 0 10 19 % T
% Val: 0 10 55 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _